IL-6 (Interleukin 6) Blockade and Heart Rate Corrected QT Interval Prolongation in COVID-19

COVID-19 and dermatologists (6)

The sixth article of COVID-19 review series is published while the virus is invading the world. In this issue, lastest findings about skin manifestations of this disease, skin diseases course, also diagnosis and treatment of COVID-19 and skin reactions due to vaccines are presented.

Curcumin and Interleukin-6 (IL-6)

Curcumin has been shown to have numerous cytotoxic effects on cancer stem cells (CSCs). This is due to its suppression of the release of cytokines, particularly interleukin (IL)-6, IL-8 and IL-1, which stimulate CSCs, and also to its effects at multiple sites along CSC pathways, such as Wnt, Notch, Hedgehog and FAK. In spite of its multiple actions targeting CSCs, curcumin has little toxicity a...

Interleukin 6 blockade in spondyloarthritis.

Association between maximal oxygen uptake and the heart rate corrected-QT interval in postmenopausal overweight women.

BACKGROUND Increased aerobic capacity can reduce the incidence of cardiovascular disease and the mortality rate. On the other hand, a prolonged heart rate corrected-QT (QTc) interval is associated with an increased risk of arrhythmias, cardiac sudden death and coronary artery disease. AIMS The association of the aerobic capacity and coronary risk factors with QTc interval was investigated in ...

Effects of cisapride on corrected QT interval, heart rate, and rhythm in infants undergoing polysomnography.

OBJECTIVE To evaluate the effects of cisapride, a prokinetic gastrointestinal drug, on the electrocardiographic QT interval, heart rate, and rhythm in infants during routine 8-hour polysomnography. Reported electrocardiogram (ECG) and rhythm disturbances in a small number of patients with the use of cisapride provided the impetus for this prospective study. STUDY DESIGN Two hundred fifty-two ...